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I just completed my first IVF after 10 failed early pregnancies conceived naturally. Two were confirmed chromosonal abnormalities, others were mostly chemical pg. I'm secondary infertility, no problems conceiving my only son at 34. Trying to decide now about donor egg.
I turned 40 this month. FSH was 18 or 20 last year, AMH 0.1. TSH was 4.2 this cycle (T3 & T4 normal, so not treated), & hubby's sperm sample came back 117 mill, 82% motile, but only 2% normal morphology for this cycle. This was a huge surprise! Previous sperm analysis had been fine, not sure how this 2% happened or if it's been a factor in my miscarriages all along.
I did estrogen in the luteal phase prior to stims, 2 weeks of estrace 2mg TV. On CD3, my LH came back 9.8, E2 was 20. I started ganirelix the that day to suppress LH & continued for all stim days. I stimmed 225 IU follistim 2x/day for exactly 10 days & E2 levels did what they were supposed to. Started with 7 follicles at 1st scan which dropped to 4 by the end. On trigger day, 2 were in the early 20's & 2 were in the late teens. I did a final injection of 450 IU of follistim along with the ovidrel. At ER only 2 eggs were retrieved, apparently 2 follicles were empty. Both eggs were successully fertilized by ICSI, but by day 2 only 1 embryo was 4 celled. We transferred on day 2 & I did a second ovidrel that night. I continued prometrium 3x/day along w/ estrace, both TV.
I've been pg many times & have always known the signs. I had mild cramping about 4-5 days after transfer & at that point started feeling mild nausea & other symptoms that I've felt previous times. About 6 days later I had massive cramping & those symptoms abruptly faded. My beta was 4 days later, negative.
What are your thoughts about my protocol, response, & overall situation? Thanks in advance for your time.
I turned 40 this month. FSH was 18 or 20 last year, AMH 0.1. TSH was 4.2 this cycle (T3 & T4 normal, so not treated), & hubby's sperm sample came back 117 mill, 82% motile, but only 2% normal morphology for this cycle. This was a huge surprise! Previous sperm analysis had been fine, not sure how this 2% happened or if it's been a factor in my miscarriages all along.
I did estrogen in the luteal phase prior to stims, 2 weeks of estrace 2mg TV. On CD3, my LH came back 9.8, E2 was 20. I started ganirelix the that day to suppress LH & continued for all stim days. I stimmed 225 IU follistim 2x/day for exactly 10 days & E2 levels did what they were supposed to. Started with 7 follicles at 1st scan which dropped to 4 by the end. On trigger day, 2 were in the early 20's & 2 were in the late teens. I did a final injection of 450 IU of follistim along with the ovidrel. At ER only 2 eggs were retrieved, apparently 2 follicles were empty. Both eggs were successully fertilized by ICSI, but by day 2 only 1 embryo was 4 celled. We transferred on day 2 & I did a second ovidrel that night. I continued prometrium 3x/day along w/ estrace, both TV.
I've been pg many times & have always known the signs. I had mild cramping about 4-5 days after transfer & at that point started feeling mild nausea & other symptoms that I've felt previous times. About 6 days later I had massive cramping & those symptoms abruptly faded. My beta was 4 days later, negative.
What are your thoughts about my protocol, response, & overall situation? Thanks in advance for your time.
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