First RE Appointment on 7/5

[Guiusc]

Hello,

I just turned 35 years in June 2011. I have experienced two miscarriages (both around seven weeks) wherein the first occurred in Dec. of 2009 and the 2nd in June of 2010. The second miscarriage was followed by some bleeding complications from June to November where I would bleed every day despite being prescribed birth control. I had a laporoscopy and D&C in Nov. 2011 which yielded no negative outcome or diagnosis other than a dangling fibroid which was removed and a description of my uterus as "serene". I have had some blood work done which revealed I had elevated levels for protein c deficiency. I was then referred to an RE hence why I have on RE appointment. My questions are:
1) What occurs at an RE appointment?
2) Does a protein C deficiency mean I cannot maintain a pregnancy?
3) Do I have a chance to maintain a pregnancy and successful birth?

Thank you for time.

[Scott Roseff MD]

Hi,

Sorry to hear about your losses. To respond to your questions:

1) I can't speak for what happens at any RE's office aside from mine. Here, I review ALL records prior to meeting with a new patient. At the consultation, I meet with my new patient face-to-face. An extensive history is taken, a physical examination is performed, and then we sit down again at which time I give a tentative diagnosis and map out a plan for any updated/new testing that should be done. For example, most recurrent loss patients haven't had sperm DNA function testing done (as abnormalities of this sperm test can result in a high chance of pregnancy failure).

2) No, a protein C deficiency doesn't necessarily result in pregnancy failure, but it has been associated with RPL and clotting and should be addressed by a board certified RE.

3) Most of my patients have a chance of maintaining a pregnancy and having a successful birth. If you see a superb, board certified RE, I would hope that would pertain to you, too.

Good luck!!!
Dr. Roseff in FL

[Guiusc]

Hi Dr. Roseff. Thank you for your speedy reply. I had my appointment with my RE today and he told me I have a single gene for MTHFR and prescribed me Fogard OS. The rest of the blood work was normal. The RE ordered an x ray of my uterus where dye will be shot through and ordered blood work to check my hormones. I have never had reproductive problems and never had an abnormal PAP smear. My questions are: 1) What are your thoughts and experiences with MTHFR clients and 2) What are your thoughts and experiences with Fogard OS? Thank you for your time and assistance.

[Scott Roseff MD]

Hi,

Single gene (heterozygous) MTHFR mutations are extremely common and meaningless regarding miscarriage. When the MTHFR IS meaningful, it causes a rise in blood levels of homocysteine. What was your homocysteine level???

Folgard is high dose folic acid, which can help lower homocysteine levels.

Looking forward to hearing how high your homocysteine level was....
Dr. Roseff in FL