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HI:
I would love to get your opinion on what i should do next given my situation. I just did my 3rd IVF stimulation and just turned 38. So far, i have been through 2 fresh cycles and 2 frozen, (with 2 blasts from each cycle). all them resulted in a BFN and 1 chemical pregnancy (2nd frozen transfer). I am an extremely high responder. I have not been diagnosed with any specific reproductive issues - MAYBE mild endo. My husband however has severe male factor issues and our only option is to do IVF/ICSI. In all cycles, i was on the Long-lupron protocol and overstimulated the first 2 times:
cycle 1 - 300 gonal-f, 1 menopur
36 eggs retrieved (28 mature), E2 over 5000, felt terrible, 4 blasts on Day 5. 2 blasts transferred on Day 5, 2 frozen and transferred in FET a few months later. - BOTH BFN.
cycle 2 - 150 gonal-f, 2 menopur
22 eggs retrieved (19 mature), E2 over 5000, felt terrible, 4 still going on Day 5. 1 blast and 1 morula transferred on Day 5 - BFN. 2 frozen and transferred in FET a few months later. - Chemical
I just completed cycle 3 (75 gonal-f, 1 menopur). after 7 days of stimulation medication, 16 eggs were retrieved and only 7 were mature. The 7 were ICSI'd and 5 fertilized. I ended up w/ 4 blasts on day 5 that they did a micro-array PGD on. it turns out only 1 was "normal" which is very discouraging and sounds like my eggs are terrible (my husband has severe male factor - can that also affect this?).
Anyway, my undestanding is that even if an embryo is "normal", since it is only ONE, there is still a very low chance that it will implant in someone my age (38 yrs old)? I wanted to ask your opinion as to whether I should bother doing the solo transfer of just one normal embryo, or if i should do another fresh cycle - which is quite expensive since i pay cash? if you thnk i should do another fresh cycle next, what would you recommend in terms of meds? is there anything that can improve egg quality? i was hoping that since i was stimmed on a low dose of meds that the quality would improve. apparently not! maybe the menopur is not good for me?
Many Thanks...
I would love to get your opinion on what i should do next given my situation. I just did my 3rd IVF stimulation and just turned 38. So far, i have been through 2 fresh cycles and 2 frozen, (with 2 blasts from each cycle). all them resulted in a BFN and 1 chemical pregnancy (2nd frozen transfer). I am an extremely high responder. I have not been diagnosed with any specific reproductive issues - MAYBE mild endo. My husband however has severe male factor issues and our only option is to do IVF/ICSI. In all cycles, i was on the Long-lupron protocol and overstimulated the first 2 times:
cycle 1 - 300 gonal-f, 1 menopur
36 eggs retrieved (28 mature), E2 over 5000, felt terrible, 4 blasts on Day 5. 2 blasts transferred on Day 5, 2 frozen and transferred in FET a few months later. - BOTH BFN.
cycle 2 - 150 gonal-f, 2 menopur
22 eggs retrieved (19 mature), E2 over 5000, felt terrible, 4 still going on Day 5. 1 blast and 1 morula transferred on Day 5 - BFN. 2 frozen and transferred in FET a few months later. - Chemical
I just completed cycle 3 (75 gonal-f, 1 menopur). after 7 days of stimulation medication, 16 eggs were retrieved and only 7 were mature. The 7 were ICSI'd and 5 fertilized. I ended up w/ 4 blasts on day 5 that they did a micro-array PGD on. it turns out only 1 was "normal" which is very discouraging and sounds like my eggs are terrible (my husband has severe male factor - can that also affect this?).
Anyway, my undestanding is that even if an embryo is "normal", since it is only ONE, there is still a very low chance that it will implant in someone my age (38 yrs old)? I wanted to ask your opinion as to whether I should bother doing the solo transfer of just one normal embryo, or if i should do another fresh cycle - which is quite expensive since i pay cash? if you thnk i should do another fresh cycle next, what would you recommend in terms of meds? is there anything that can improve egg quality? i was hoping that since i was stimmed on a low dose of meds that the quality would improve. apparently not! maybe the menopur is not good for me?
Many Thanks...
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